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Okuyama Hiroyuki

  • Faculty of Medicine
  • University Hospital
  • Associate Professor
Last Updated :2026/06/24

Researcher Information

Research funding number

  • 50448362

J-Global ID

Research Interests

  • 腫瘍   tumor   

Research Areas

  • Life sciences / Internal medicine - General

Academic & Professional Experience

  • 2018/01 - Today  Kagawa UniversityUniversity Hospital, Faculty of Medicine
  • 2016/04 - 2018/01  Kagawa UniversityUniversity Hospital, Faculty of Medicine
  • 2013 - 2015  国立がん研究センター東病院 肝胆膵内科, がん専門修練医
  • 2010 - 2013  国立がん研究センター東病院 肝胆膵内科, レジデント
  • 2009 - 2010  Kagawa UniversityUniversity Hospital, Faculty of Medicine
  • 2006 - 2009  Kagawa UniversityUniversity Hospital, Faculty of Medicine

Education

  • 2011/04 - 2017/03  Kagawa Medical University
  • 2008/04 - 2015/03  Kagawa University

Association Memberships

  • THE JAPANESE SOCIETY OF INTERNAL MEDICINE   日本臨床腫瘍学会   THE JAPAN SOCIETY OF ULTRASONICS IN MEDICINE   JAPANESE SOCIETY OF GASTROENTEROLOGY   日本家族性腫瘍学会   

Published Papers

Conference Activities & Talks

  • A phase II study of everolimus in patients with unresectable pancreatic neuroendocrine carcinoma refractory or intolerant to platinum-contained chemotherapy  [Not invited]
    OKUYAMA Hiroyuki
    ESMO 2018  2018/10

MISC

  • NEN肝転移に対するインターベンショナルラジオロジー
    奥山 浩之; 喜田 行洋; 村上 あきつ; 大北 仁裕; 辻 晃仁; 奥坂 拓志  外科 = Surgery : 臨床雑誌  83-  (12)  1336  -1340  2021/11
  • Exploring the Cause and the Preventive Measures of Feeding Tube Occlusion during the Administration of ENSURE LIQUlD
    田井達也; 山口佳津騎; 渡邊政博; 山本高成; 香西真衣; 本田由紀; 元木貴大; 田中裕章; 加地雅人; 森照茂; 星川広史; 大北仁裕; 奥山浩之; 辻晃仁; 小坂信二; 芳地一  医療薬学  45-  (9)  522‐527  -527  2019/09
  • 奥山 浩之; 羽床 琴音; 大北 仁裕; 西内 崇将; 辻 晃仁  内科 = Internal medicine : 臨床雑誌  124-  (2)  1607  -1611  2019/08
  • 漢方薬(補剤)を用いたがん患者の免疫能改善及び栄養改善効果に関する検討
    西内崇将; 村上あきつ; 大北裕仁; 奥山浩之; 辻晃仁  日本癌治療学会学術集会(Web)  56th-  ROMBUNNO.P56‐4 (WEB ONLY)  -4  2018/10
  • 経口摂取不良な胃がん患者に対するFOLFOX療法の初期経験
    奥山浩之; 村上あきつ; 大北仁裕; 西内崇将; 辻晃仁  日本消化器病学会四国支部例会プログラム・抄録集  110th-  57  -57  2018/10
  • 頭頸部扁平上皮癌高用量CDDP併用放射線療法におけるがん薬物療法専門医介入の後方視的検討
    大北仁裕; 森照茂; 岸野毅日人; 村上あきつ; 奥山浩之; 西内崇将; 高橋重雄; 柴田徹; 星川広司; 辻晃仁  頭頸部癌  44-  (2)  144  2018/05
  • 薬剤による経腸栄養剤の経管チューブ閉塞回避のための一考察と検討
    田井達也; 山口佳津騎; 山本高成; 香西真衣; 本田由紀; 元木貴大; 田中裕章; 加地雅人; 森照茂; 星川広史; 大北仁裕; 奥山浩之; 辻晃仁; 小坂信二; 芳地一  日本医療薬学会年会講演要旨集(Web)  28-  2018
  • 奥山浩之; 大北仁裕; 辻晃仁  日本大腸肛門病学会雑誌(Web)  71-  (10)  387‐392(J‐STAGE)  -392  2018
  • だるさのため同一体位保持困難なオピオイド使用患者のCTガイド下生検術にデクスメデトミジンによる鎮静が有効であった1症例
    村上 あきつ; 中條 浩介; 奥山 浩之; 石川 一朗; 大林 由美子; 宮本 沙美; 鈴木 聖; 今出 政代; 重田 宏恵; 本多 美枝; 辻 晃仁  Palliative Care Research  12-  (Suppl.)  S513  -S513  2017/06
  • 添付文書未記載の薬剤相互作用を緩和ケアチームでの情報共有にて対応し,早期の症状改善が得られた1例~クリゾチニブカプセルとグレープフルーツ~
    鈴木聖; 元木貴大; 田中裕章; 阿部寿子; 今出政代; 宮本沙美; 奥山浩之; 中條浩介; 小坂信二; 辻晃仁; 芳地一  日本緩和医療薬学会年会プログラム・要旨集  11th-  222  2017
  • Hiroyuki Okuyama; Masafumi Ikeda; Hideaki Takahashi; Izumi Ohno; Yusuke Hashimoto; Shuichi Mitsunaga; Yasunari Sakamoto; Shunsuke Kondo; Chigusa Morizane; Hideki Ueno; Tatsushi Kobayashi; Yasuaki Arai; Takuji Okusaka  ONCOLOGY  92-  (6)  353  -359  2017  [Refereed]
  • 切除不能進行・再発大腸癌に対するTAS‐102,Regorafenib投与の後方視的検討
    大北仁裕; 大北仁裕; 佐竹悠良; 奥山浩之; 西内崇将; 籏智幸政; 古武剛; 古武剛; 亀井敬子; 辻晃仁; 辻晃仁  日本臨床腫瘍学会学術集会(CD-ROM)  14th-  ROMBUNNO.O1‐8‐5  2016
  • 当院における膵がん新規標準化学療法の安全性に関する検討
    奥山浩之; 大北仁裕; 西内崇将; 亀井敬子; 辻晃仁  日本臨床腫瘍学会学術集会(CD-ROM)  14th-  ROMBUNNO.P1‐041  2016
  • Safety and efficacy of modified FOLFIRINOX in patients with metastatic pancreatic cancer
    Kazuo Watanabe; Hideaki Takahashi; Kumiko Umemoto; Hiroyuki Okuyama; Yusuke Hashimoto; Izumi Ohno; Satoshi Shimizu; Shuichi Mitsunaga; Takuji Okusaka; Masafumi Ikeda  ANNALS OF ONCOLOGY  26-  88  -88  2015/11
  • S100A8/A9 as a potent serological marker in monitoring the activity of chemotherapy in pancreatic cancer.
    Shuichi Mitsunaga; Masafumi Ikeda; Satoshi Shimizu; Izumi Ohno; Hideaki Takahashi; Hiroyuki Okuyama; Yusuke Hashimoto; Kazuo Watanabe; Kumiko Umemoto; Atsushi Ochiai  JOURNAL OF CLINICAL ONCOLOGY  33-  (15)  2015/05
  • S100P tumor-marker response to chemotherapy in patients with advanced pancreatic cancer.
    Shuichi Mitsunaga; Kumiko Umemoto; Kazuo Watanabe; Hiroyuki Okuyama; Yusuke Hashimoto; Hideaki Takahashi; Izumi Ohno; Satoshi Shimizu; Atsushi Ochiai; Masafumi Ikeda  JOURNAL OF CLINICAL ONCOLOGY  33-  (3)  2015/01
  • Association of gemcitabine (GEM) efficacy on unresectable invasive pancreatic carcinoma with intraductal papillary mucinous neoplasms.
    Yusuke Hashimoto; Satoshi Shimizu; Kazuo Watanabe; Kumiko Umemoto; Hiroyuki Okuyama; Hideaki Takahashi; Izumi Ohno; Shuichi Mitsunaga; Masafumi Ikeda  JOURNAL OF CLINICAL ONCOLOGY  33-  (3)  2015/01
  • The identification of the age effects in 1,287 patients with biliary tract cancer.
    Kumiko Umemoto; Shuichi Mitsunaga; Kazuo Watanabe; Hiroyuki Okuyama; Yusuke Hashimoto; Hideaki Takahashi; Izumi Ohno; Satoshi Shimizu; Masafumi Ikeda  JOURNAL OF CLINICAL ONCOLOGY  33-  (3)  2015/01
  • 皮下埋め込み型中心静脈リザーバーの活用
    辻晃仁; 辻晃仁; 大北仁裕; 大北仁裕; 佐竹悠良; 古武剛; 渡邊貴紀; 籏智幸政; 奥山浩之; 西内崇将  日本臨床腫瘍学会学術集会(CD-ROM)  13th-  ROMBUNNO.PD3-3  2015
  • Hiroyuki Okuyama; Masafumi Ikeda; Akiko Kuwahara; Hideaki Takahashi; Lzumi Ohno; Satoshi Shimizu; Shuichi Mitsunaga; Shoichi Senda; Takuji Okusaka  ONCOLOGY  88-  (4)  241  -246  2015  [Refereed]
  • Hideaki Takahashi; Akiko Kuwahara; Hiroyuki Okuyama; Izumi Ohno; Satoshi Shimizu; Shuichi Mitsunaga; Akira Shinohara; Misaki Kobayashi; Takuji Okusaka; Masafumi Ikeda  ANNALS OF ONCOLOGY  25-  2014/10
  • Masafumi Ikeda; Hiroyuki Okuyama; Hideaki Takahashi; Izumi Ohno; Satoshi Shimizu; Shuichi Mitsunaga; Takuji Okusaka  ANNALS OF ONCOLOGY  25-  2014/10
  • Shuichi Mitsunaga; Masafumi Ikeda; Izumi Ohno; Satoshi Shimizu; Hideaki Takahashi; Hiroyuki Okuyama; Akiko Kuwahara; Atsushi Ochiai  ANNALS OF ONCOLOGY  25-  2014/10
  • Masafumi Ikeda; Hiroyuki Okuyama; Hideaki Takahashi; Izumi Ohno; Satoshi Shimizu; Shuichi Mitsunaga; Chigusa Morizane; Takuji Okusaka  ANNALS OF ONCOLOGY  25-  2014/10
  • Efficacy of prophylactic minocycline treatment for skin toxicities induced by erlotinib plus gemcitabine in advanced pancreatic cancer patients
    Akira Shinohara; Hiroyuki Okuyama; Akiko Kuwahara; Misaki Kobayashi; Hideaki Takahashi; Izumi Ohno; Satoshi Shimizu; Shuichi Mitsunaga; Shinichiro Saitoh; Masafumi Ikeda  JOURNAL OF CLINICAL ONCOLOGY  32-  (3)  2014/01
  • The time trends of gallbladder cancer and cholangiocarcinoma in 1,047 patients
    Shuichi Mitsunaga; Masafumi Ikeda; Satoshi Shimizu; Izumi Ohno; Hideaki Takahashi; Hiroyuki Okuyama; Akiko Kuwahara; Atsushi Ochiai  JOURNAL OF CLINICAL ONCOLOGY  32-  (3)  2014/01
  • Influence of obstructive jaundice on chemotherapy in patients with unresectable biliary tract cancer
    Satoshi Shimizu; Shuichi Mitsunaga; Izumi Ohno; Hideaki Takahashi; Hiroyuki Okuyama; Akiko Kuwahara; Takuji Okusaka; Masafumi Ikeda  JOURNAL OF CLINICAL ONCOLOGY  32-  (3)  2014/01
  • Characterization of patients with high serum level of IL-6 in advanced pancreatic cancer.
    Tomofumi Miura; Shuichi Mitsunaga; Satoshi Shimizu; Izumi Ohno; Hideaki Takahashi; Hiroyuki Okuyama; Akiko Kuwahara; Masafumi Ikeda  JOURNAL OF CLINICAL ONCOLOGY  32-  (3)  2014/01
  • A phase I trial of GBS-01 for advanced pancreatic cancer refractory to gemcitabine.
    Masafumi Ikeda; Akihiro Sato; Nobuo Mochizuki; Kayo Toyosaki; Chika Miyoshi; Rumi Fujioka; Shuichi Mitsunaga; Satoshi Shimizu; Izumi Ohno; Hideaki Takahashi; Hiroyuki Okuyama; Hiromi Hasegawa; Shogo Nomura; Toshiki Ohkubo; Satoshi Yomoda; Satoshi Kishino; Hiroyasu Esumi  JOURNAL OF CLINICAL ONCOLOGY  31-  (15)  2013/05
  • Akiko Kuwahara; Shuichi Mitsunaga; Izumi Ohno; Satoshi Shimizu; Hideaki Takahashi; Hiroyuki Okuyama; Takuji Okusaka; Hideki Ueno  JOURNAL OF CLINICAL ONCOLOGY  30-  (4)  2012/02
  • Aortic Root Dilatation as a Marker of Subclinical Left Ventricular Diastolic Dysfunction in Patients with Cardiovascular Risk Factors
    MASUGATA Hisashi; SENDA Shoichii; MURAO Koji; OKUYAMA Hiroyuki; INUKAI Michio; HOSOMI Naohisa; IWADO Yasuyoshi; NOMA Takahisa; KOHNO Masakazu; HIMOTO Takashi; GODA Fuminori  J Int Med Res.  39-  (1)  64  -70  2011
  • 合田文則; 犬飼道雄; 奥山浩之; 樋本尚志; 舛形尚; 千田彰一  静脈経腸栄養  25-  (3)  823  -829  2010
  • 医療面接教育用DVDを用いた医療面接講義の影響についての検討
    舛形 尚; 岡田 宏基; 余島 侑子; 奥山 浩之; 山上 あゆむ; 犬飼 道雄; 河野 武章; 樋本 尚志; 合田 文則; 千田 彰一  医学教育  40-  (Suppl.)  84  -84  2009/07
  • 共用試験OSCE後の臨床実習における模擬患者による医療面接実習の意義と問題点
    舛形 尚; 岡田 宏基; 余島 侑子; 合田 文則; 河野 武章; 山上 あゆむ; 奥山 浩之; 樋本 尚志; 千田 彰一  医学教育  40-  (3)  175  -179  2009/06
  • Masugata Hisashi; Okada Hiroki; Yoshima Yukiko; 合田文則; 河野武章; 山上あゆむ; 奥山浩之; 樋本尚志; 千田彰一  医学教育  40-  (3)  175  -179  2009
  • 臨床実習における模擬患者による医療面接授業の意義と問題点
    舛形 尚; 岡田 宏基; 余島 侑子; 合田 文則; 樋本 尚志; 宮下 浩明; 河野 武章; 奥山 浩之; 山上 あゆむ; 千田 彰一  医学教育  39-  (Suppl.)  56  -56  2008/07
  • Relationship between echocardiographic findings and atherosclerosis in retinal arteries
    MASUGATA Hisashi; SENDA Shoichi; YAMAGAMI Ayumu; OKUYAMA Hiroyuki; KOHNO Takeaki  Japanese journal of medical ultrasonics = 超音波医学  35-  S584  2008/04
  • A Newly Developed Index of Cardiac Aging
    MASUGATA Hisashi; SENDA Shoich; OKUYAMA Hiroyuki; YOSHIKAWA Kay  Journal of medical ultrasonics = 超音波医学  34-  S585  2007/04
  • PE-488 Cardiac Diastolic Dysfunction is Related to Aging and the Duration of Diabetes in Normotensive Patients with Type 2 Diabetes Mellitus(Diabetes/Obesity/Metabolic syndrome-07, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
    Masugata Hisashi; Senda Shoichi; Goda Fuminori; Himoto Takashi; Miyashita Hiroaki; Okuyama Hiroyuki; Yoshihara Yumiko; Yoshikawa Kei; Fujita Norihiro; Kohno Masakazu  Circulation journal : official journal of the Japanese Circulation Society  71-  446  -446  2007/03
  • 臨床実習における模擬患者による医療面接授業の意義と問題点
    舛形 尚; 岡田 宏基; 余島 侑子; 合田 文則; 樋本 尚志; 宮下 浩明; 河野 武章; 奥山 浩之; 千田 彰一  総合診療医学  12-  (1)  87  -87  2007/02
  • 胃瘻からの半固形栄養材の注入が安全にできるデバイスの開発
    合田文則; 奥山浩之; 樋本尚志; 舛形 尚; 千田彰一; 門田千晶; 多田達史; 藤井映子; 河野武章; 名古将太郎; 橋本康子  在宅医療と内視鏡治療  11-  (1)  74  -80  2007
  • 自ら総合診療部外来を受診した男性痩せ症の1例
    奥山 浩之; 山上 あゆむ; 河野 武章; 岩藤 泰慶; 樋本 尚志; 合田 文則; 岡田 宏基; 千田 彰一  総合診療医学  11-  (1)  75  -75  2006/02
  • Body Structure for Improvement of Vehicle Crashworthiness
    OKUYAMA Hiroyuki  自動車技術  56-  (11)  48  -53  2002/11

Research Grants & Projects

  • A new index of" cardiac age" derived from echocardiography : A study for brain-cardio-renal connection and organ damages of hypertension.
    Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research
    Date (from‐to) : 2009 -2011 
    Author : MASUGATA Hisashi; SENDA Shoichi; GODA Fuminori
     
    Although pulse wave velocity is the primary indicator of arteriosclerosis and is widely used as an index of vascular age in anti-aging medicine, no index is available to quantify cardiac age. We proposed a" cardiac age" index and sought to clarify its clinical significance. Enrolled in the study were patients with atherosclerosis-related diseases. These patients were divided into normotensive and hypertensive patients. Echocardiography was performed, and brachial-ankle pulse wave velocity(baPWV) was measured using an automatic waveform analyzer. The index of cardiac age was determined as 1000×VSot/ BSA/(VS-AO), where VSot(mm) was the ventricular septal thickness at the left ventricular outflow tract, BSA(m^2) was the body surface area, and VS-AO(degrees) was the angle between the basal ventricular septum and the ascending aorta. The index of cardiac aging correlated significantly with age in both the normotensive and hypertensive patients, and these correlations were closer than those between transmitral E/ A(early to atrial velocity) ratio and age in normotensive and hypertensive patients. The slope between age(x axis) and the index of cardiac age(y axis) was greater in hypertensive(1. 50) than normotensive(1. 32) patients. Stepwise regression analysis showed that age, the presence of hypertension, the left ventricular mass index, the left ventricular end-diastolic dimension, the dimension of left atrium, and the ratio of E to A(E/ A) were independently associated with the index of cardiac age. The index was also significantly correlated with baPWV. The proposed index of cardiac age can quantitatively assess cardiac morphological changes due to aging and/ or hypertension and may be a useful marker of peripheral arterial stiffening.
  • 膵がんの予後に関する研究
  • prognosis of pancreatic cnacaer

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