Saheki Takanobu

Researcher Information

Degree

• Bachelor（2016/03 Kagawa University）

Research funding number

• 40884664

J-Global ID

• 202001016978264727

Research Interests

• 脂肪毒性   

Research Areas

• Life sciences / Metabolism and endocrinology

Academic & Professional Experience

• 香川大学医学部付属病院 検査部香川大学医学部付属病院 検査部助教

Education

•        -   Kagawa University  医学部

Association Memberships

• 内科学会   糖尿病学会   内分泌学会   

Published Papers

• Acute Thyroid Swelling After Fine-Needle Aspiration in von Willebrand Disease: Case Report and Literature Review

  Takanobu Saheki; Toshihiro Kobayashi; Kensaku Fukunaga; Hitomi Imachi; Koji Murao

  Cureus Springer Science and Business Media LLC 2168-8184 2025/05
• Enhancing Postprandial Hyperglycemia Detection Sensitivity in Individuals With Impaired Glucose Tolerance by Incorporating 1,5-Anhydroglucitol Into Diagnostic Testing: A Multicenter and Prospective Observational Study

  Kensaku Fukunaga; Toshihiro Kobayashi; Hitomi Imachi; Shin Horikawa; Yasuyoshi Iwata; Takanobu Saheki; Takafumi Yoshimura; Seisuke Sato; Rathana Ly; Koji Murao

  Cureus Springer Science and Business Media LLC 2168-8184 2025/05
• A Case of TAFRO Syndrome with Massive Bilateral Adrenal Hemorrhage.

  Toshihiro Kobayashi; Hitomi Imachi; Kensaku Fukunaga; Takanobu Saheki; Takafumi Yoshimura; Kurumi Komori; Wenyi Jiang; Haotian Zhang; Rathana Ly; Ryou Ishikawa; Reiji Haba; Hiroaki Dobashi; Koji Murao

  Internal medicine (Tokyo, Japan) 2025/03
• Exendin-4 Increases Scavenger Receptor Class BI Expression via Activation of AMPK/FoxO1 in Human Vascular Endothelial Cells

  Jingya Lyu; Hitomi Imachi; Kensaku Fukunaga; Seisuke Sato; Toshihiro Kobayashi; Takanobu Saheki; Salimah Japar; Hisakazu Iwama; Yuta Matsumura; Miyo Ozaki; Takafumi Yoshimura; Koji Murao

  Current Issues in Molecular Biology MDPI AG 44 (11) 5474 - 5484 2022/11
• Knowledge of diabetes and the practice of diabetes self-management during Ramadan fasting among patients with type 2 diabetes in Malaysia

  Salimah Japar; Swee Leong Ong; Zamri Muhamed; Kensaku Fukunaga; Toshihiro Kobayashi; Hitomi Imachi; Seisuke Sato; Takanobu Saheki; Tomohiro Ibata; Takafumi Yoshimura; Kim Lam Soh; Koji Murao

  Diabetes & Metabolic Syndrome: Clinical Research & Reviews Elsevier BV 16 (11) 102655 - 102655 1871-4021 2022/11
• A pilot study on the effect of d-allulose on postprandial glucose levels in patients with type 2 diabetes mellitus during Ramadan fasting

  Salimah Japar; Kensaku Fukunaga; Toshihiro Kobayashi; Hitomi Imachi; Seisuke Sato; Takanobu Saheki; Tomohiro Ibata; Takafumi Yoshimura; Kim Lam Soh; Swee Leong Ong; Zamri Muhamed; Koji Murao

  Diabetology & Metabolic Syndrome Springer Science and Business Media LLC 14 (1) 2022/06
• Effects of 2-Methoxyestradiol, a Main Metabolite of Estradiol on Hepatic ABCA1 Expression in HepG2 Cells.

  Tomohiro Ibata; Jingya Lyu; Hitomi Imachi; Kensaku Fukunaga; Seisuke Sato; Toshihiro Kobayashi; Takanobu Saheki; Takafumi Yoshimura; Koji Murao

  Nutrients 14 (2) 2022/01
• HDL promotes adiponectin gene expression via the CAMKK/CAMKIV pathway.

  Toshihiro Kobayashi; Hitomi Imachi; Kensaku Fukunaga; Jingya Lyu; Seisuke Sato; Takanobu Saheki; Tomohiro Ibata; Mari Matsumoto; Salimah B Japar; Koji Murao

  Journal of molecular endocrinology 68 (2) 89 - 98 2022/01
• 尿崩症を契機に発見されたIgG4関連疾患によると思われる大動脈周囲炎の一例

  高場 萌; 吉村 崇史; 佐伯 岳信; 佐藤 誠祐; 小林 俊博; 井端 智裕; 井町 仁美; 村尾 孝児

  日本内分泌学会雑誌 (一社)日本内分泌学会 97 (4) 992 - 992 0029-0661 2021/12
• 自己免疫性膵炎経過観察中に高浸透圧高血糖症候群を起こした一例

  佐伯 岳信; 高場 萌; 吉村 崇史; 小林 俊博; 佐藤 誠祐; 井端 智裕; 井町 仁美; 村尾 孝児

  日本内分泌学会雑誌 (一社)日本内分泌学会 97 (4) 997 - 997 0029-0661 2021/12
• Oxidized LDL Downregulates ABCA1 Expression via MEK/ERK/LXR Pathway in INS-1 Cells.

  Jingya Lyu; Kensaku Fukunaga; Hitomi Imachi; Seisuke Sato; Toshihiro Kobayashi; Takanobu Saheki; Tomohiro Ibata; Takafumi Yoshimura; Hisakazu Iwama; Koji Murao

  Nutrients 13 (9) 2021/08
• Nivolumab-induced hypophysitis followed by acute-onset type 1 diabetes with renal cell carcinoma: a case report

  Fumi Kikuchi; Takanobu Saheki; Hitomi Imachi; Toshihiro Kobayashi; Kensaku Fukunaga; Tomohiro Ibata; Seisuke Sato; Natsuki Ban; Jingya Lyu; Salimah Japar; Koji Murao

  Journal of Medical Case Reports Springer Science and Business Media LLC 15 (1) 2021/04
• Successful Therapy Using Pasireotide Long-acting Release for Cushing's Disease Merged with Biochemical Acromegaly.

  Kensaku Fukunaga; Hitomi Imachi; Seisuke Sato; Toshihiro Kobayashi; Yuki Yoshioka; Takanobu Saheki; Natsuki Ban; Kurumi Urushihara; Jingya Lyu; Tao Dong; Ryou Ishikawa; Kyuichi Kadota; Reiji Haba; Naoko Inoshita; Koji Murao

  Internal medicine (Tokyo, Japan) 60 (7) 1047 - 1053 2021/04
• AGEs inhibit scavenger receptor class B type I gene expression via Smad1 in HUVECs.

  Hiromi Nagata; Jingya Lyu; Hitomi Imachi; Kensaku Fukunaga; Seisuke Sato; Toshihiro Kobayashi; Takanobu Saheki; Kayoko Seo; Japar B Salimah; Hisakazu Iwama; Ryuichi Sakamoto; Yoshihiro Ogawa; Koji Murao

  Journal of molecular endocrinology 66 (3) 223 - 231 2021/03
• Ectopic Cortisol-producing Adrenocortical Adenoma Detected by 131I-6β-iodomethyl-norcholesterol Scintigraphy

  Seisuke Sato; Hitomi Imachi; Toshihiro Kobayashi; Kensaku Fukunaga; Jingya Lyu; Tao Dong; Yuuki Yoshioka; Takanobu Saheki; Youko Fukata; Natsuki Ban; Kurumi Urushihara; Kyuuichi Kadota; Koji Murao

  Internal Medicine Japanese Society of Internal Medicine 59 (14) 1731 - 1734 0918-2918 2020/07
• Role of ATP-binding cassette transporter A1 in suppressing lipid accumulation by glucagon-like peptide-1 agonist in hepatocytes

  Jingya Lyu; Hitomi Imachi; Kensaku Fukunaga; Seisuke Sato; Toshihiro Kobayashi; Tao Dong; Takanobu Saheki; Mari Matsumoto; Hisakazu Iwama; Huanxiang Zhang; Koji Murao

  Molecular Metabolism 34 16 - 26 2020/04
• Treatment with 2-methoxyestradiol increases endothelial nitric oxide synthase activity via scavenger receptor class BI in human umbilical vein endothelial cells

  Tao Dong; Seisuke Sato; Jingya Lyu; Hitomi Imachi; Toshihiro Kobayashi; Kensaku Fukunaga; Takanobu Saheki; Hisakazu Iwama; Guoxing Zhang; Koji Murao

  Molecular Human Reproduction 26 (6) 441 - 451 1360-9947 2020/04
• Co-existing of Neuromyelitis Optica and Fulminant Type 1 Diabetes.

  Takanobu Saheki; Hitomi Imachi; Tomohiro Ibata; Kensuke Fukunaga; Yuki Yoshioka; Toshihiro Kobayashi; Seisuke Sato; Kazuko Mizumoto; Takuo Yoshimoto; Jingya Lyu; Tao Dong; Koji Murao

  Internal medicine (Tokyo, Japan) 58 (13) 1913 - 1916 2019/07 [Refereed]
  

Research Grants & Projects

• NMDA受容体刺激が脂肪毒性をもたらす原因となり得るか

Social Contribution

• 世界糖尿病デー 2021年度

  Date (from-to) : 2021/11/01-2021/11/30

  Role : Organizing member
• 世界糖尿病デー

  Date (from-to) : 2018/11

  Role : Organizing member

  Event, Program, Title : 世界糖尿病デー

Other link

researchmap

https://researchmap.jp/1236