Researchers Database

Ayano Tada

  • Faculty of Medicine
  • School of Medicine
  • Assistant Professor
Last Updated :2026/07/24

Researcher Information

J-Global ID

Research Interests

  • 病原性   フソバクテリウム   口腔細菌   

Research Areas

  • Life sciences / Bacteriology

Academic & Professional Experience

  • 2017/07 - Today  Kagawa UniversityFaculty of Medicine助教
  • 2016/04 - 2017/06  Kagawa UniversityFaculty of Medicine協力研究員
  • 2016/04 - 2017/06  番町歯科クリニック常勤歯科医師
  • 2011/04 - 2012/03  Kagawa UniversityUniversity Hospital, Faculty of Medicine研修医

Education

  • 2012/04 - 2016/03  Kagawa University  Graduate School of Medicine  医学系研究科
  •        - 2011/03  Kyushu University  School of Dentistry

Association Memberships

  • JAPANESE SOCIETY OF ORAL THERAPEUTICS AND PHARMACOLOGY   JAPANESE SOCIETY FOR ORAL HEALTH   THE JAPANESE CANCER ASSOCIATION   JAPANESE SOCIETY OF CHEMOTHERAPY   THE JAPANESE ASSOCIATION FOR INFECTIOUS DISEASES   JAPANESE SOCIETY FOR BACTERIOLOGY   

Published Papers

Research Grants & Projects

  • 歯周病細菌のデンタルプラーク内環境適応と病原性との関連
    日本学術振興会:科学研究費助成事業 基盤研究(C)
    Date (from‐to) : 2023/04 -2026/03 
    Author : 多田 彩乃
  • Analysis of the molecular mechanism of fusobacterial coaggregation with other oral bacteria
    Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Early-Career Scientists
    Date (from‐to) : 2020/04 -2022/03 
    Author : Tada Ayano
     
    Fusobacterium nulceatum co-aggregates with other oral microbes. We found that the culture supernatant of A. naeslundii enhanced the growth and autoaggregation of F. nucleatum. Transcriptome analysis of F. nucleatum revealed that the expression of the genes for D-fructose utilization was up-regulated in response to the culture supernatant of A. naeslundii. In consistent with the finding, D-fructose promoted the growth of F. nucleatum and biofilm formation. Furthermore, the adherence of F. nucleatum to Ca9-22, human gingival cancer cell, when the bacterium was cultured in BHIS medium containing D-fructose. These results indicate that the adaptation of F. nucleatum to environmental changes such as nutritional status closely associates with the formation of complex bacterial consortium in subgingival region, resulting in the progression of periodontal diseases.
  • 歯肉縁下プラーク形成に関与するフソバクテリウムの共凝集分子の網羅的解析
    日本学術振興会:科学研究費補助金
    Date (from‐to) : 2018 -2020/03 
    Author : 多田 彩乃

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